EXOC3

GENE INFORMATION

? »

Gene name

EXOC3 (HGNC Symbol)

Synonyms

SEC6L1, Sec6p

Description

Exocyst complex component 3 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. [provided by RefSeq, Jul 2008]

Chromosome

5

Cytoband

p15.33

Chromosome location (bp)

443273 - 472052

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000180104 (version 75.37)

Entrez gene

11336

UniProt

O60645 (UniProt - Evidence at protein level)

neXtProt

NX_O60645

Antibodypedia

EXOC3 antibodies
 

PROTEIN VIEW

? »
 
 
 
EXOC3-001
 
EXOC3-002
 
EXOC3-003
 
EXOC3-004
 
EXOC3-201
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

EXOC3-001 ENSP00000425587
ENST00000512944
O60645
Show all »
Show » Show » 745 85.6 No 0
EXOC3-002 ENSP00000424404
ENST00000515601
D6RB59
Show all »
Show » Show » 462 53.2 No 0
EXOC3-003 ENSP00000423435
ENST00000503889
Show » Show » 473 54.9 No 0
EXOC3-004 ENSP00000422596
ENST00000508022
D6RBR9
Show all »
Show » Show » 69 7.8 No 0
EXOC3-201 ENSP00000323377
ENST00000315013
O60645
Show all »
Show » Show » 745 85.6 No 0