SLC47A2

GENE INFORMATION

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Gene name

SLC47A2 (HGNC Symbol)

Synonyms

FLJ31196, MATE2, MATE2-K

Description

Solute carrier family 47 (multidrug and toxin extrusion), member 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a protein belonging to a family of transporters involved in excretion of toxic electrolytes, both endogenous and exogenous, through urine and bile. This transporter family shares homology with the bacterial MATE (multidrug and toxin extrusion) protein family responsible for drug resistance. This gene is one of two members of the MATE transporter family located near each other on chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

Chromosome

17

Cytoband

p11.2

Chromosome location (bp)

19581601 - 19622292

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000180638 (version 75.37)

Entrez gene

146802

UniProt

Q86VL8 (UniProt - Evidence at protein level)

neXtProt

NX_Q86VL8

Antibodypedia

SLC47A2 antibodies
 

PROTEIN VIEW

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SLC47A2-001
 
SLC47A2-002
 
SLC47A2-008
 
SLC47A2-010
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SLC47A2-001 ENSP00000338084
ENST00000350657
Q86VL8
Show all »
Show » Show » 580 62.7 No >9
SLC47A2-002 ENSP00000326671
ENST00000325411
Q86VL8
Show all »
Show » Show » 602 65.1 No >9
SLC47A2-008 ENSP00000391848
ENST00000433844
C9JAE6
Show all »
Show » Show » 363 39.3 No >9
SLC47A2-010 ENSP00000458694
ENST00000574239
Q86VL8
Show all »
Show » Show » 219 23.3 No 4