LIPF

GENE INFORMATION

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Gene name

LIPF (HGNC Symbol)

Synonyms

HGL, HLAL

Description

Lipase, gastric (HGNC Symbol)

Entrez gene summary

This gene encodes gastric lipase, an enzyme involved in the digestion of dietary triglycerides in the gastrointestinal tract, and responsible for 30% of fat digestion processes occurring in human. It is secreted by gastric chief cells in the fundic mucosa of the stomach, and it hydrolyzes the ester bonds of triglycerides under acidic pH conditions. The gene is a member of a conserved gene family of lipases that play distinct roles in neutral lipid metabolism. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]

Chromosome

10

Cytoband

q23.31

Chromosome location (bp)

90424198 - 90438571

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000182333 (version 75.37)

Entrez gene

8513

UniProt

P07098 (UniProt - Evidence at protein level)

neXtProt

NX_P07098

Antibodypedia

LIPF antibodies
 

PROTEIN VIEW

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LIPF-001
 
LIPF-002
 
LIPF-004
 
LIPF-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

LIPF-001 ENSP00000238983
ENST00000238983
P07098
Show all »
Show » Show » 398 45.2 Yes 0
LIPF-002 ENSP00000348101
ENST00000355843
P07098
Show all »
Show » Show » 375 42.8 Yes 0
LIPF-004 ENSP00000377900
ENST00000394375
P07098
Show all »
Show » Show » 408 46.4 Yes 0
LIPF-006 ENSP00000477140
ENST00000608620
Show » Show » 365 41.7 No 0