CLDN5

GENE INFORMATION

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Gene name

CLDN5 (HGNC Symbol)

Synonyms

AWAL, BEC1, CPETRL1, TMVCF

Description

Claudin 5 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2008]

Chromosome

22

Cytoband

q11.21

Chromosome location (bp)

19510547 - 19515068

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000184113 (version 75.37)

Entrez gene

7122

UniProt

O00501 (UniProt - Evidence at protein level)

neXtProt

NX_O00501

Antibodypedia

CLDN5 antibodies
 

PROTEIN VIEW

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CLDN5-001
 
CLDN5-002
 
CLDN5-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CLDN5-001 ENSP00000385477
ENST00000406028
O00501
Show all »
Show » Show » 303 31.6 No 4
CLDN5-002 ENSP00000400612
ENST00000413119
O00501
Show all »
Show » Show » 303 31.6 No 4
CLDN5-003 ENSP00000384554
ENST00000403084
O00501
Show all »
Show » Show » 303 31.6 No 4