KLHL33

TISSUE ATLAS

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Gene description

Kelch-like family member 33

RNA tissue category

Tissue enriched (skeletal muscle).

Protein summary

Detected at High or Medium expression level in 18 of 80 analyzed normal tissue cell types.

Protein expression

Salivary ducts, gastrointestinal tract, exocrine pancreas, renal tubules, hematopoietic cells, smooth muscle cells, thyroid and adrenal glands displayed moderate cytoplasmic positivity. Additional membranous staining was observed in intestinal tract. Respiratory epithelial cells in nasopharynx and glandular cells in breast were strongly stained. The liver, cells in CNS, squamous epithelia, pancreatic islets, uterus and cervix were negative.

Predicted localization

Intracellular

Protein evidence

Evidence at transcript level

Protein reliability

Uncertain based on 1 antibody.
Liver
Colon
Kidney
Testis
Lymph node
Cerebral cortex
Breast
RNA Protein

Expression (FPKM)

Organ system

Localization (score)

100
50
0

h
m
l
n

Liver and pancreas
Liver
Gallbladder
Pancreas
Digestive tract (GI-tract)
N/A Oral mucosa
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Appendix
Colon
Rectum
Urinary tract (Kidney and bladder)
Kidney
Urinary bladder
Male reproductive system (Male tissues)
Testis
N/A Epididymis
Prostate
N/A Seminal vesicle
Breast and female reproductive system
N/A Breast
N/A Vagina
N/A Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Skin and soft tissues
Skin
Adipose tissue
Skeletal muscle
Smooth muscle
N/A Soft tissue
Blood and immune system (Hematopoietic)
Bone marrow
Lymph node
Tonsil
Spleen
Central nervous system (Brain)
Cerebral cortex
N/A Hippocampus
N/A Lateral ventricle
N/A Cerebellum
Endocrine glands
Thyroid gland
N/A Parathyroid gland
Adrenal gland
Respiratory system (Lung)
N/A Nasopharynx
N/A Bronchus
Lung
Cardiovascular system
Heart muscle

Antibodies in assay

HPA056560