SLC52A2

GENE INFORMATION

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Gene name

SLC52A2 (HGNC Symbol)

Synonyms

D15Ertd747e, FLJ11856, GPCR41, GPR172A, hRFT3, PAR1, RFVT2

Description

Solute carrier family 52 (riboflavin transporter), member 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a membrane protein which belongs to the riboflavin transporter family. In humans, riboflavin must be obtained by intestinal absorption because it cannot be synthesized by the body. The water-soluble vitamin riboflavin is processed to the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) which then act as intermediaries in many cellular metabolic reactions. Paralogous members of the riboflavin transporter gene family are located on chromosomes 17 and 20. Unlike other members of this family, this gene has higher expression in brain tissue than small intestine. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. Mutations in this gene have been associated with Brown-Vialetto-Van Laere syndrome 2 - an autosomal recessive progressive neurologic disorder characterized by deafness, bulbar dysfunction, and axial and limb hypotonia. [provided by RefSeq, Jul 2012]

Chromosome

8

Cytoband

q24.3

Chromosome location (bp)

145577795 - 145584932

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000185803 (version 75.37)

Entrez gene

79581

UniProt

Q9HAB3 (UniProt - Evidence at protein level)

neXtProt

NX_Q9HAB3

Antibodypedia

SLC52A2 antibodies
 

PROTEIN VIEW

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 « 
 
SLC52A2-001
 
SLC52A2-002
 
SLC52A2-003
 
SLC52A2-004
 
SLC52A2-005
 
SLC52A2-008
 
SLC52A2-009
 
SLC52A2-010
 
SLC52A2-011
 
SLC52A2-012
 
SLC52A2-201
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SLC52A2-001 ENSP00000333638
ENST00000329994
Q9HAB3
Show all »
Show » Show » 445 45.8 No >9
SLC52A2-002 ENSP00000435820
ENST00000530047
Q9HAB3
Show all »
Show » Show » 445 45.8 No >9
SLC52A2-003 ENSP00000385961
ENST00000402965
Q9HAB3
Show all »
Show » Show » 445 45.8 No >9
SLC52A2-004 ENSP00000436768
ENST00000532887
Q9HAB3
Show all »
Show » Show » 445 45.8 No >9
SLC52A2-005 ENSP00000431965
ENST00000534725
E9PIX2
Show all »
Show » 172 18.3 No 4
SLC52A2-008 ENSP00000436917
ENST00000526779
E9PPS0
Show all »
Show » 87 9.3 No 1
SLC52A2-009 ENSP00000434728
ENST00000527078
Q9HAB3
Show all »
Show » Show » 445 45.8 No >9
SLC52A2-010 ENSP00000434239
ENST00000524541
E9PRC3
Show all »
Show » 69 7.4 No 1
SLC52A2-011 ENSP00000433583
ENST00000526338
E9PKE4
Show all »
Show » 170 17.3 Yes 2
SLC52A2-012 ENSP00000433796
ENST00000526752
E9PJC1
Show all »
Show » 111 11.7 Yes 0
SLC52A2-201 ENSP00000440400
ENST00000540505
F5GXA8
Show all »
Show » 357 36.4 Yes 7