GABRA5

GENE INFORMATION

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Gene name

GABRA5

Synonyms

Description

Gamma-aminobutyric acid (GABA) A receptor, alpha 5 (HGNC Symbol)

Entrez gene summary

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described. [provided by RefSeq, Jul 2008]

Chromosome

15

Cytoband

q12

Chromosome location (bp)

27111510 - 27194354

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000186297 (version 75.37)

Entrez gene

2558

UniProt

P31644 (UniProt - Evidence at protein level)

neXtProt

NX_P31644

Antibodypedia

GABRA5 antibodies
 

PROTEIN VIEW

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GABRA5-001
 
GABRA5-002
 
GABRA5-004
 
GABRA5-005
 
GABRA5-007
 
GABRA5-008
 
GABRA5-009
 
GABRA5-010
 
GABRA5-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GABRA5-001 ENSP00000335592
ENST00000335625
P31644
Show all »
Show » Show » 462 52.1 Yes 4
GABRA5-002 ENSP00000347557
ENST00000355395
P31644
Show all »
Show » Show » 462 52.1 Yes 4
GABRA5-004 ENSP00000451527
ENST00000554038
G3V408
Show all »
Show » Show » 86 9.7 Yes 0
GABRA5-005 ENSP00000450806
ENST00000554596
G3V2Q9
Show all »
Show » Show » 149 17.2 Yes 0
GABRA5-007 ENSP00000450932
ENST00000555060
Show » 16 1.8 No 0
GABRA5-008 ENSP00000450717
ENST00000554599
G3V2K2
Show all »
Show » Show » 166 19.2 Yes 0
GABRA5-009 ENSP00000450529
ENST00000554083
G3V296
Show all »
Show » Show » 86 10.1 No 0
GABRA5-010 ENSP00000450653
ENST00000555182
G3V2G8
Show all »
Show » Show » 166 19.1 No 0
GABRA5-201 ENSP00000382953
ENST00000400081
P31644
Show all »
Show » Show » 462 52.1 Yes 4