CLCNKA

GENE INFORMATION

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Gene name

CLCNKA (HGNC Symbol)

Synonyms

hClC-Ka

Description

Chloride channel, voltage-sensitive Ka (HGNC Symbol)

Entrez gene summary

This gene is a member of the CLC family of voltage-gated chloride channels. The encoded protein is predicted to have 12 transmembrane domains, and requires a beta subunit called barttin to form a functional channel. It is thought to function in salt reabsorption in the kidney and potassium recycling in the inner ear. The gene is highly similar to CLCNKB, which is located 10 kb downstream from this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

p36.13

Chromosome location (bp)

16345370 - 16360545

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000186510 (version 75.37)

Entrez gene

1187

UniProt

P51800 (UniProt - Evidence at protein level)

neXtProt

NX_P51800

Antibodypedia

CLCNKA antibodies
 

PROTEIN VIEW

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CLCNKA-001
 
CLCNKA-002
 
CLCNKA-007
 
CLCNKA-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CLCNKA-001 ENSP00000332771
ENST00000331433
P51800
Show all »
Show » Show » 687 75.3 No >9
CLCNKA-002 ENSP00000364844
ENST00000375692
P51800
Show all »
Show » Show » 686 75.2 No >9
CLCNKA-007 ENSP00000414445
ENST00000439316
P51800
Show all »
Show » Show » 644 70.5 No >9
CLCNKA-201 ENSP00000410353
ENST00000420078
P51800
Show all »
Show » Show » 686 75.2 No >9