DEFB105A

GENE INFORMATION

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Gene name

DEFB105A (HGNC Symbol)

Synonyms

DEFB-5, DEFB105

Description

Defensin, beta 105A (HGNC Symbol)

Entrez gene summary

Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 105, DEFB105A and DEFB105B, in tail-to-tail orientation. This gene, DEFB105A, represents the more centromeric copy. [provided by RefSeq, Oct 2014]

Chromosome

8

Cytoband

p23.1

Chromosome location (bp)

7679488 - 7681411

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000186562 (version 75.37)

Entrez gene

245908

UniProt

Q8NG35 (UniProt - Evidence at transcript level)

neXtProt

NX_Q8NG35

Antibodypedia

DEFB105A antibodies
 

PROTEIN VIEW

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DEFB105A-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DEFB105A-001 ENSP00000334330
ENST00000334773
Q8NG35
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