DEFB106A

GENE INFORMATION

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Gene name

DEFB106A (HGNC Symbol)

Synonyms

DEFB-6, DEFB106

Description

Defensin, beta 106A (HGNC Symbol)

Entrez gene summary

Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 106, DEFB106A and DEFB106B, in head-to-head orientation. This gene, DEFB106A, represents the more centromeric copy. [provided by RefSeq, Oct 2014]

Chromosome

8

Cytoband

p23.1

Chromosome location (bp)

7682694 - 7686575

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000186579 (version 75.37)

Entrez gene

245909

UniProt

Q8N104 (UniProt - Evidence at protein level)

neXtProt

NX_Q8N104

Antibodypedia

DEFB106A antibodies
 

PROTEIN VIEW

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DEFB106A-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DEFB106A-001 ENSP00000335307
ENST00000335186
Q8N104
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