KRT16

GENE INFORMATION

? »

Gene name

KRT16 (HGNC Symbol)

Synonyms

NEPPK

Description

Keratin 16 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region of chromosome 17q12-q21. This keratin has been coexpressed with keratin 14 in a number of epithelial tissues, including esophagus, tongue, and hair follicles. Mutations in this gene are associated with type 1 pachyonychia congenita, non-epidermolytic palmoplantar keratoderma and unilateral palmoplantar verrucous nevus. [provided by RefSeq, Jul 2008]

Chromosome

17

Cytoband

q21.2

Chromosome location (bp)

39766030 - 39772151

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000186832 (version 75.37)

Entrez gene

3868

UniProt

P08779 (UniProt - Evidence at protein level)

neXtProt

NX_P08779

Antibodypedia

KRT16 antibodies
 

PROTEIN VIEW

? »
 
 
 
KRT16-001
 
KRT16-003
 
KRT16-004
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KRT16-001 ENSP00000301653
ENST00000301653
P08779
Show all »
Show » Show » 473 51.3 No 0
KRT16-003 ENSP00000467124
ENST00000593067
K7ENW6
Show all »
Show » Show » 162 18.6 No 0
KRT16-004 ENSP00000467105
ENST00000590990
K7ENV3
Show all »
Show » Show » 49 4.6 No 0