EFCAB6

GENE INFORMATION

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Gene name

EFCAB6 (HGNC Symbol)

Synonyms

dJ185D5.1, DJBP, FLJ23588, HSCBCIP1, KIAA1672

Description

EF-hand calcium binding domain 6 (HGNC Symbol)

Entrez gene summary

This gene encodes a protein which directly binds the oncogene DJ-1 and androgen receptor to form a ternary complex in cells. This binding protein recruits histone-deacetylase complexes in order to repress transcription activity of androgen receptor. This protein may also play a role in spermatogenesis and fertilization. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

Chromosome

22

Cytoband

q13.2

Chromosome location (bp)

43924624 - 44208217

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000186976 (version 75.37)

Entrez gene

64800

UniProt

Q5THR3 (UniProt - Evidence at protein level)

neXtProt

NX_Q5THR3

Antibodypedia

EFCAB6 antibodies
 

PROTEIN VIEW

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EFCAB6-001
 
EFCAB6-003
 
EFCAB6-010
 
EFCAB6-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

EFCAB6-001 ENSP00000379533
ENST00000396231
Q5THR3
Show all »
Show » Show » 1349 155.8 No 0
EFCAB6-003 ENSP00000348391
ENST00000356087
B0QYI5
Show all »
Show » Show » 200 23.1 No 0
EFCAB6-010 ENSP00000262726
ENST00000262726
Q5THR3
Show all »
Show » Show » 1501 172.9 No 0
EFCAB6-201 ENSP00000351219
ENST00000358439
B4DKR4
Show all »
Show » Show » 243 28.2 No 0