LILRA5

GENE INFORMATION

? »

Gene name

LILRA5 (HGNC Symbol)

Synonyms

CD85, CD85f, ILT11, LILRB7, LIR9

Description

Leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family. LIR family members are known to have activating and inibitory functions in leukocytes. Crosslink of this receptor protein on the surface of monocytes has been shown to induce calcium flux and secretion of several proinflammatory cytokines, which suggests the roles of this protein in triggering innate immune responses. This gene is one of the leukocyte receptor genes that form a gene cluster on the chromosomal region 19q13.4. Four alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

Chromosome

19

Cytoband

q13.42

Chromosome location (bp)

54818353 - 54824409

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000187116 (version 75.37)

Entrez gene

353514

UniProt

A6NI73 (UniProt - Evidence at protein level)

neXtProt

NX_A6NI73

Antibodypedia

LILRA5 antibodies
 

PROTEIN VIEW

? »
 
 
 
LILRA5-001
 
LILRA5-002
 
LILRA5-201
 
LILRA5-202
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

LILRA5-001 ENSP00000301219
ENST00000301219
A6NI73
Show all »
Show » Show » 299 32.8 No 1
LILRA5-002 ENSP00000302948
ENST00000346508
A6NI73
Show all »
Show » Show » 287 31.5 No 1
LILRA5-201 ENSP00000404236
ENST00000432233
A6NI73
Show all »
Show » Show » 265 29.1 No 0
LILRA5-202 ENSP00000389499
ENST00000446712
A6NI73
Show all »
Show » Show » 253 27.9 No 0