ISG15

GENE INFORMATION

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Gene name

ISG15 (HGNC Symbol)

Synonyms

G1P2, IFI15, UCRP

Description

ISG15 ubiquitin-like modifier (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a ubiquitin-like protein that is conjugated to intracellular target proteins upon activation by interferon-alpha and interferon-beta. Several functions have been ascribed to the encoded protein, including chemotactic activity towards neutrophils, direction of ligated target proteins to intermediate filaments, cell-to-cell signaling, and antiviral activity during viral infections. While conjugates of this protein have been found to be noncovalently attached to intermediate filaments, this protein is sometimes secreted. [provided by RefSeq, Dec 2012]

Chromosome

1

Cytoband

p36.33

Chromosome location (bp)

948803 - 949920

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000187608 (version 75.37)

Entrez gene

9636

UniProt

P05161 (UniProt - Evidence at protein level)

neXtProt

NX_P05161

Antibodypedia

ISG15 antibodies
 

PROTEIN VIEW

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ISG15-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ISG15-001 ENSP00000368699
ENST00000379389
P05161
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