MESP2

GENE INFORMATION

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Gene name

MESP2 (HGNC Symbol)

Synonyms

bHLHc6, SCDO2

Description

Mesoderm posterior 2 homolog (mouse) (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the bHLH family of transcription factors and plays a key role in defining the rostrocaudal patterning of somites via interactions with multiple Notch signaling pathways. This gene is expressed in the anterior presomitic mesoderm and is downregulated immediately after the formation of segmented somites. This gene also plays a role in the formation of epithelial somitic mesoderm and cardiac mesoderm. Mutations in the MESP2 gene cause autosomal recessive spondylocostal dystosis 2 (SCD02). [provided by RefSeq, Oct 2008]

Chromosome

15

Cytoband

q26.1

Chromosome location (bp)

90303822 - 90321982

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000188095 (version 75.37)

Entrez gene

145873

UniProt

Q0VG99 (UniProt - Evidence at protein level)

neXtProt

NX_Q0VG99

Antibodypedia

MESP2 antibodies
 

PROTEIN VIEW

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MESP2-001
 
MESP2-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MESP2-001 ENSP00000342392
ENST00000341735
Q0VG99
Show all »
Show » Show » 397 41.8 No 0
MESP2-002 ENSP00000452998
ENST00000560219
H0YKZ5
Show all »
99 10.6 No 0