PPP3R2

TISSUE ATLAS

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Gene description

Protein phosphatase 3, regulatory subunit B, beta

RNA tissue category

Tissue enriched (testis).

Protein summary

Detected at High or Medium expression level in 31 of 77 analyzed normal tissue cell types.

Protein expression

Most normal tissues displayed weak to moderate cytoplasmic positivity. Gall bladder, breast, spermatids in testis, Leydig cells and skeletal myocytes were strongly stained. Stomach exhibited strong cytoplasmic and membranous staining. Strong cytoplasmic and nuclear immunoreactivity was observed in neuronal cells. The liver, lung, placenta, exocrine glandular cells, thyroid, glial cells and prostate were negative. Caution: Based on antibody targeting proteins from multiple genes.

Protein class

FDA approved drug targets

Predicted localization

Intracellular

Protein evidence

Evidence at transcript level

Protein reliability

Uncertain based on 1 antibody.
Liver
Colon
Kidney
Testis
Lymph node
Cerebral cortex
Lateral ventricle
RNA Protein

Expression (FPKM)

Organ system

Localization (score)

100
50
0

h
m
l
n

Liver and pancreas
Liver
Gallbladder
Pancreas
Digestive tract (GI-tract)
N/A Oral mucosa
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Appendix
Colon
Rectum
Urinary tract (Kidney and bladder)
Kidney
Urinary bladder
Male reproductive system (Male tissues)
Testis
N/A Epididymis
Prostate
N/A Seminal vesicle
Breast and female reproductive system
N/A Breast
N/A Vagina
N/A Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Skin and soft tissues
Skin
Adipose tissue
Skeletal muscle
Smooth muscle
N/A Soft tissue
Blood and immune system (Hematopoietic)
Bone marrow
Lymph node
Tonsil
Spleen
Central nervous system (Brain)
Cerebral cortex
N/A Hippocampus
N/A Lateral ventricle
N/A Cerebellum
Endocrine glands
Thyroid gland
N/A Parathyroid gland
Adrenal gland
Respiratory system (Lung)
N/A Nasopharynx N/A
N/A Bronchus
Lung
Cardiovascular system
Heart muscle

Antibodies in assay

HPA047157

Other gene match

HPA047157 PPP3R1 - ENSG00000221823 [92%]
RP11-474G23.1 - ENSG00000273398 [92%]