SELL

GENE INFORMATION

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Gene name

SELL (HGNC Symbol)

Synonyms

CD62L, hLHRc, LAM-1, LAM1, Leu-8, LNHR, LSEL, Lyam-1, LYAM1, PLNHR

Description

Selectin L (HGNC Symbol)

Entrez gene summary

This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009]

Chromosome

1

Cytoband

q24.2

Chromosome location (bp)

169659808 - 169680839

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000188404 (version 75.37)

Entrez gene

6402

UniProt

P14151 (UniProt - Evidence at protein level)

neXtProt

NX_P14151

Antibodypedia

SELL antibodies
 

PROTEIN VIEW

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SELL-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SELL-001 ENSP00000236147
ENST00000236147
P14151
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