KAZN

GENE INFORMATION

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Gene name

KAZN (HGNC Symbol)

Synonyms

FLJ43806, KAZRIN, KIAA1026

Description

Kazrin, periplakin interacting protein (HGNC Symbol)

Entrez gene summary

This gene encodes a protein that plays a role in desmosome assembly, cell adhesion, cytoskeletal organization, and epidermal differentiation. This protein co-localizes with desmoplakin and the cytolinker protein periplakin. In general, this protein localizes to the nucleus, desmosomes, cell membrane, and cortical actin-based structures. Some isoforms of this protein also associate with microtubules. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity has not been verified. [provided by RefSeq, Aug 2011]

Chromosome

1

Cytoband

p36.21

Chromosome location (bp)

14925200 - 15444539

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000189337 (version 75.37)

Entrez gene

23254

UniProt

Q674X7 (UniProt - Evidence at protein level)

neXtProt

NX_Q674X7

Antibodypedia

KAZN antibodies
 

PROTEIN VIEW

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KAZN-001
 
KAZN-003
 
KAZN-005
 
KAZN-006
 
KAZN-007
 
KAZN-201
 
KAZN-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KAZN-001 ENSP00000365198
ENST00000376030
Q674X7
Show all »
Show » Show » 775 86.4 No 0
KAZN-003 ENSP00000354727
ENST00000361144
Q674X7
Show all »
Show » Show » 415 46.2 No 0
KAZN-005 ENSP00000365196
ENST00000376028
B0QYQ6
Show all »
Show » Show » 166 19.2 No 0
KAZN-006 ENSP00000426015
ENST00000503743
Q674X7
Show all »
Show » Show » 421 46.8 No 0
KAZN-007 ENSP00000383601
ENST00000400797
Q674X7
Show all »
Show » Show » 327 37 No 0
KAZN-201 ENSP00000383602
ENST00000400798
Q674X7
Show all »
Show » Show » 327 37 No 0
KAZN-202 ENSP00000391728
ENST00000422387
Q674X7
Show all »
Show » Show » 421 46.8 No 0