ADH1B

GENE INFORMATION

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Gene name

ADH1B (HGNC Symbol)

Synonyms

ADH2

Description

Alcohol dehydrogenase 1B (class I), beta polypeptide (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This encoded protein, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]

Chromosome

4

Cytoband

q23

Chromosome location (bp)

100226121 - 100242558

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000196616 (version 75.37)

Entrez gene

125

UniProt

P00325 (UniProt - Evidence at protein level)

neXtProt

NX_P00325

Antibodypedia

ADH1B antibodies
 

PROTEIN VIEW

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ADH1B-001
 
ADH1B-004
 
ADH1B-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ADH1B-001 ENSP00000306606
ENST00000305046
P00325
Show all »
Show » Show » 375 39.8 No 0
ADH1B-004 ENSP00000425998
ENST00000506651
Show » 13 1.4 No 0
ADH1B-201 ENSP00000378351
ENST00000394887
A8MYN5
Show all »
Show » Show » 335 35.4 No 0