TUBA3C

GENE INFORMATION

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Gene name

TUBA3C (HGNC Symbol)

Synonyms

bA408E5.3, TUBA2

Description

Tubulin, alpha 3c (HGNC Symbol)

Entrez gene summary

Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene is an alpha tubulin gene that encodes a protein 99% identical to the mouse testis-specific Tuba3 and Tuba7 gene products. This gene is located in the 13q11 region, which is associated with the genetic diseases Clouston hidrotic ectodermal dysplasia and Kabuki syndrome. [provided by RefSeq, Jul 2008]

Chromosome

13

Cytoband

q12.11

Chromosome location (bp)

19747910 - 19755992

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000198033 (version 75.37)

Entrez gene

7278

UniProt

Q13748 (UniProt - Evidence at protein level)

neXtProt

NX_Q13748

Antibodypedia

TUBA3C antibodies
 

PROTEIN VIEW

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TUBA3C-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TUBA3C-002 ENSP00000382982
ENST00000400113
Q13748
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