TUBB3

GENE INFORMATION

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Gene name

TUBB3 (HGNC Symbol)

Synonyms

beta-4

Description

Tubulin, beta 3 class III (HGNC Symbol)

Entrez gene summary

This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Oct 2010]

Chromosome

16

Cytoband

q24.3

Chromosome location (bp)

89985573 - 90002500

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000198211 (version 75.37)

Entrez gene

10381

UniProt

neXtProt

Antibodypedia

TUBB3 antibodies
 

PROTEIN VIEW

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TUBB3-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TUBB3-001 ENSP00000451560
ENST00000556922
Q9BV28
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