PEG3

GENE INFORMATION

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Gene name

PEG3 (HGNC Symbol)

Synonyms

KIAA0287, ZKSCAN22, ZNF904, ZSCAN24

Description

Paternally expressed 3 (HGNC Symbol)

Entrez gene summary

In human, ZIM2 and PEG3 are treated as two distinct genes though they share multiple 5' exons and a common promoter and both genes are paternally expressed (PMID:15203203). Alternative splicing events connect their shared 5' exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. In contrast, in other mammals ZIM2 does not undergo imprinting and, in mouse, cow, and likely other mammals as well, the ZIM2 and PEG3 genes do not share exons. Human PEG3 protein belongs to the Kruppel C2H2-type zinc finger protein family. PEG3 may play a role in cell proliferation and p53-mediated apoptosis. PEG3 has also shown tumor suppressor activity and tumorigenesis in glioma and ovarian cells. Alternative splicing of this PEG3 gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Sep 2009]

Chromosome

19

Cytoband

q13.43

Chromosome location (bp)

57321445 - 57352096

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000198300 (version 75.37)

Entrez gene

5178

UniProt

Q9GZU2 (UniProt - Evidence at protein level)

neXtProt

NX_Q9GZU2

Antibodypedia

PEG3 antibodies
 

PROTEIN VIEW

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PEG3-001
 
PEG3-002
 
PEG3-003
 
PEG3-004
 
PEG3-005
 
PEG3-006
 
PEG3-009
 
PEG3-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PEG3-001 ENSP00000472395
ENST00000599534
Q9GZU2
Show all »
Show » Show » 1588 180.8 No 0
PEG3-002 ENSP00000469486
ENST00000599577
Q9GZU2
Show all »
Show » Show » 1588 180.8 No 0
PEG3-003 ENSP00000326581
ENST00000326441
Q9GZU2
Show all »
Show » Show » 1588 180.8 No 0
PEG3-004 ENSP00000473190
ENST00000598410
Q9GZU2
Show all »
Show » Show » 1464 166.1 No 0
PEG3-005 ENSP00000472402
ENST00000593695
Q9GZU2
Show all »
Show » Show » 1462 166 No 0
PEG3-006 ENSP00000470467
ENST00000600833
M0QZD4
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Show » Show » 395 45.7 No 0
PEG3-009 ENSP00000469144
ENST00000594389
M0QXG1
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Show » Show » 36 4 No 0
PEG3-201 ENSP00000403051
ENST00000423103
Q9GZU2
Show all »
Show » Show » 1588 180.8 No 0