TPM2

GENE INFORMATION

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Gene name

TPM2 (HGNC Symbol)

Synonyms

AMCD1, DA1, NEM4

Description

Tropomyosin 2 (beta) (HGNC Symbol)

Entrez gene summary

This gene encodes beta-tropomyosin, a member of the actin filament binding protein family, and mainly expressed in slow, type 1 muscle fibers. Mutations in this gene can alter the expression of other sarcomeric tropomyosin proteins, and cause cap disease, nemaline myopathy and distal arthrogryposis syndromes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009]

Chromosome

9

Cytoband

p13.3

Chromosome location (bp)

35681989 - 35691017

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000198467 (version 75.37)

Entrez gene

7169

UniProt

P07951 (UniProt - Evidence at protein level)

neXtProt

NX_P07951

Antibodypedia

TPM2 antibodies
 

PROTEIN VIEW

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TPM2-001
 
TPM2-002
 
TPM2-005
 
TPM2-006
 
TPM2-008
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TPM2-001 ENSP00000367542
ENST00000378292
P07951
Show all »
Show » Show » 284 33 No 0
TPM2-002 ENSP00000354219
ENST00000360958
P07951
Show all »
Show » Show » 284 32.9 No 0
TPM2-005 ENSP00000367550
ENST00000378300
Q5TCU8
Show all »
Show » 322 36.7 No 0
TPM2-006 ENSP00000367541
ENST00000329305
Q5TCU3
Show all »
Show » 284 32.8 No 0
TPM2-008 ENSP00000475952
ENST00000607559
U3KQK2
Show all »
Show » 111 12.9 No 0