MUC2

GENE INFORMATION

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Gene name

MUC2

Synonyms

Description

Mucin 2, oligomeric mucus/gel-forming (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. The protein encoded by this gene is secreted and forms an insoluble mucous barrier that protects the gut lumen. The protein polymerizes into a gel of which 80% is composed of oligosaccharide side chains by weight. The protein features a central domain containing tandem repeats rich in threonine and proline that varies between 50 and 115 copies in different individuals. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jul 2008]

Chromosome

11

Cytoband

p15.5

Chromosome location (bp)

1074875 - 1104419

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000198788 (version 75.37)

Entrez gene

4583

UniProt

Q02817 (UniProt - Evidence at protein level)

neXtProt

NX_Q02817

Antibodypedia

MUC2 antibodies
 

PROTEIN VIEW

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MUC2-001
 
MUC2-201
 
MUC2-202
 
MUC2-203
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MUC2-001 ENSP00000415183
ENST00000441003
E7EUV1
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Show » Show » 2817 303.4 Yes 0
MUC2-201 ENSP00000331373
ENST00000333592
H0Y2U6
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Show » Show » 278 28 No 0
MUC2-202 ENSP00000351956
ENST00000359061
Q02817
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Show » Show » 1780 191.9 Yes 0
MUC2-203 ENSP00000354885
ENST00000361558
H0Y317
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Show » 409 45.4 No 0