CCL27

GENE INFORMATION

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Gene name

CCL27 (HGNC Symbol)

Synonyms

ALP, CTACK, CTAK, ESkine, ILC, PESKY, SCYA27, skinkine

Description

Chemokine (C-C motif) ligand 27 (HGNC Symbol)

Entrez gene summary

This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation. [provided by RefSeq, Sep 2014]

Chromosome

9

Cytoband

p13.3

Chromosome location (bp)

34661877 - 34664045

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000213927 (version 75.37)

Entrez gene

10850

UniProt

Q9Y4X3 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y4X3

Antibodypedia

CCL27 antibodies
 

PROTEIN VIEW

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CCL27-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CCL27-001 ENSP00000259631
ENST00000259631
Q9Y4X3
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