GANC

GENE INFORMATION

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Gene name

GANC

Synonyms

Description

Glucosidase, alpha; neutral C (HGNC Symbol)

Entrez gene summary

Glycosyl hydrolase enzymes hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. This gene encodes a member of glycosyl hydrolases family 31. This enzyme hydrolyses terminal, non-reducing 1,4-linked alpha-D-glucose residues and releases alpha-D-glucose. This is a key enzyme in glycogen metabolism and its gene localizes to a chromosomal region (15q15) that is associated with susceptibility to diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2014]

Chromosome

15

Cytoband

q15.1

Chromosome location (bp)

42565431 - 42645864

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000214013 (version 75.37)

Entrez gene

2595

UniProt

Q8TET4 (UniProt - Evidence at transcript level)

neXtProt

NX_Q8TET4

Antibodypedia

GANC antibodies
 

PROTEIN VIEW

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GANC-001
 
GANC-002
 
GANC-003
 
GANC-005
 
GANC-007
 
GANC-008
 
GANC-009
 
GANC-010
 
GANC-012
 
GANC-013
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GANC-001 ENSP00000326227
ENST00000318010
Q8TET4
Show all »
Show » Show » 914 104.3 No 0
GANC-002 ENSP00000454747
ENST00000566442
H3BN99
Show all »
Show » Show » 357 40.3 No 0
GANC-003 ENSP00000399557
ENST00000440615
E7EWB6
Show all »
Show » Show » 282 31.6 No 0
GANC-005 ENSP00000454578
ENST00000562170
H3BMW3
Show all »
Show » Show » 68 7.9 No 0
GANC-007 ENSP00000455872
ENST00000567784
H3BRQ6
Show all »
Show » 37 4.3 No 0
GANC-008 ENSP00000454816
ENST00000561871
Show » 9 1 No 0
GANC-009 ENSP00000454449
ENST00000562859
H3BMM3
Show all »
Show » Show » 140 15.8 No 0
GANC-010 ENSP00000456360
ENST00000570013
H3BRQ6
Show all »
Show » 37 4.3 No 0
GANC-012 ENSP00000457604
ENST00000567596
H3BUE8
Show all »
Show » Show » 113 12.6 No 0
GANC-013 ENSP00000455511
ENST00000566690
H3BPX5
Show all »
Show » Show » 103 11.5 No 0