PRPS1L1

GENE INFORMATION

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Gene name

PRPS1L1 (HGNC Symbol)

Synonyms

PRPS3, PRPSL

Description

Phosphoribosyl pyrophosphate synthetase 1-like 1 (HGNC Symbol)

Entrez gene summary

This intronless gene is specifically expressed in the testis, and encodes a protein that is highly homologous to the two subunits of phosphoribosylpyrophosphate synthetase encoded by human X-linked genes, PRPS1 and PRPS2. These enzymes convert pyrimidine, purine or pyridine bases to the corresponding ribonucleoside monophosphates. In vitro transcription/translation and site-directed mutagenesis studies indicate that translation of this mRNA initiates exclusively at a non-AUG (ACG) codon. [provided by RefSeq, Jul 2008]

Chromosome

7

Cytoband

p21.1

Chromosome location (bp)

18066405 - 18067486

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000229937 (version 75.37)

Entrez gene

221823

UniProt

neXtProt

Antibodypedia

PRPS1L1 antibodies
 

PROTEIN VIEW

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PRPS1L1-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PRPS1L1-001 ENSP00000424595
ENST00000506618
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