TXNDC5

GENE INFORMATION

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Gene name

TXNDC5 (HGNC Symbol)

Synonyms

EndoPDI, ERp46, FLJ21353, FLJ90810, Hcc-2, MGC3178, PDIA15

Description

Thioredoxin domain containing 5 (endoplasmic reticulum) (HGNC Symbol)

Entrez gene summary

This gene encodes a protein-disulfide isomerase. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream MUTED (muted homolog) gene. [provided by RefSeq, Dec 2010]

Chromosome

6

Cytoband

p24.3

Chromosome location (bp)

7881483 - 8026646

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000239264 (version 75.37)

Entrez gene

81567

UniProt

Q8NBS9 (UniProt - Evidence at protein level)

neXtProt

NX_Q8NBS9

Antibodypedia

TXNDC5 antibodies
 

PROTEIN VIEW

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TXNDC5-001
 
TXNDC5-003
 
TXNDC5-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TXNDC5-001 ENSP00000369081
ENST00000379757
Q8NBS9
Show all »
Show » Show » 432 47.6 Yes 0
TXNDC5-003 ENSP00000420784
ENST00000473453
Q8NBS9
Show all »
Show » Show » 324 36.2 No 0
TXNDC5-201 ENSP00000442453
ENST00000539054
Q86UY0
Show all »
Show » Show » 360 40.4 No 0