ARPC4

GENE INFORMATION

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Gene name

ARPC4 (HGNC Symbol)

Synonyms

ARC20, p20-Arc

Description

Actin related protein 2/3 complex, subunit 4, 20kDa (HGNC Symbol)

Entrez gene summary

This gene encodes one of seven subunits of the human Arp2/3 protein complex. This complex controls actin polymerization in cells and has been conserved throughout eukaryotic evolution. This gene encodes the p20 subunit, which is necessary for actin nucleation and high-affinity binding to F-actin. Alternative splicing results in multiple transcript variants. Naturally occurring read-through transcription exists between this gene and the downstream tubulin tyrosine ligase-like family, member 3 (TTLL3), which results in the production of a fusion protein. [provided by RefSeq, Nov 2010]

Chromosome

3

Cytoband

p25.3

Chromosome location (bp)

9834179 - 9849410

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000241553 (version 75.37)

Entrez gene

10093

UniProt

P59998 (UniProt - Evidence at protein level)

neXtProt

NX_P59998

Antibodypedia

ARPC4 antibodies
 

PROTEIN VIEW

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ARPC4-001
 
ARPC4-002
 
ARPC4-003
 
ARPC4-005
 
ARPC4-009
 
ARPC4-010
 
ARPC4-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ARPC4-001 ENSP00000380431
ENST00000397261
P59998
Show all »
Show » Show » 168 19.7 No 0
ARPC4-002 ENSP00000395085
ENST00000440787
F8WDD7
Show all »
Show » Show » 113 13.1 No 0
ARPC4-003 ENSP00000414751
ENST00000417500
F8WDW3
Show all »
Show » Show » 44 4.9 No 0
ARPC4-005 ENSP00000432235
ENST00000498623
P59998
Show all »
Show » Show » 78 9.6 No 0
ARPC4-009 ENSP00000473435
ENST00000485273
R4GN08
Show all »
Show » Show » 77 9.4 No 0
ARPC4-010 ENSP00000388169
ENST00000433034
P59998
Show all »
Show » Show » 187 21.6 No 0
ARPC4-201 ENSP00000287613
ENST00000287613
P59998
Show all »
Show » Show » 78 9.6 No 0