ARPC1A

GENE INFORMATION

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Gene name

ARPC1A (HGNC Symbol)

Synonyms

Arc40, SOP2Hs, SOP2L

Description

Actin related protein 2/3 complex, subunit 1A, 41kDa (HGNC Symbol)

Entrez gene summary

This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1B. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]

Chromosome

7

Cytoband

q22.1

Chromosome location (bp)

98923521 - 98985787

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000241685 (version 75.37)

Entrez gene

10552

UniProt

Q92747 (UniProt - Evidence at protein level)

neXtProt

NX_Q92747

Antibodypedia

ARPC1A antibodies
 

PROTEIN VIEW

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ARPC1A-001
 
ARPC1A-003
 
ARPC1A-009
 
ARPC1A-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ARPC1A-001 ENSP00000262942
ENST00000262942
Q92747
Show all »
Show » Show » 370 41.6 No 0
ARPC1A-003 ENSP00000412879
ENST00000441989
F8WFD3
Show all »
Show » Show » 53 6.1 No 0
ARPC1A-009 ENSP00000408711
ENST00000432786
E9PF58
Show all »
Show » Show » 279 30.9 No 0
ARPC1A-201 ENSP00000408578
ENST00000432884
B4DLQ7
Show all »
Show » Show » 345 38.6 No 0