C2orf15

GENE INFORMATION

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Gene name

C2orf15 (HGNC Symbol)

Synonyms

MGC29762

Description

Chromosome 2 open reading frame 15 (HGNC Symbol)

Entrez gene summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Alternative splicing results in multiple transcript variants. Pseudogenes corresponding to this gene are found on chromosomes 6p and 12p. Read-through transcription also exists between this gene and the neighboring upstream lipoyltransferase 1 (LIPT1) gene. [provided by RefSeq, Mar 2011]

Chromosome

2

Cytoband

q11.2

Chromosome location (bp)

99757948 - 99939204

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000241962 (version 75.37)

Entrez gene

51263

UniProt

neXtProt

Antibodypedia

C2orf15 antibodies
 

PROTEIN VIEW

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C2orf15-001
 
C2orf15-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

C2orf15-001 ENSP00000390891
ENST00000424491
Show » 191 21.8 No 0
C2orf15-201 ENSP00000420959
ENST00000512183
Show » 161 18.5 No 0