WFDC6

GENE INFORMATION

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Gene name

WFDC6 (HGNC Symbol)

Synonyms

C20orf171, dJ461P17.11, WAP6

Description

WAP four-disulfide core domain 6 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the telomeric cluster. Read-through transcription exists between this gene and the upstream SPINLW1 (serine peptidase inhibitor-like, with Kunitz and WAP domains 1) gene. [provided by RefSeq, Nov 2010]

Chromosome

20

Cytoband

q13.12

Chromosome location (bp)

44162835 - 44168134

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000243543 (version 75.37)

Entrez gene

140870

UniProt

Q9BQY6 (UniProt - Evidence at transcript level)

neXtProt

NX_Q9BQY6

Antibodypedia

WFDC6 antibodies
 

PROTEIN VIEW

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WFDC6-001
 
WFDC6-002
 
WFDC6-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

WFDC6-001 ENSP00000361755
ENST00000372670
Q9BQY6
Show all »
Show » Show » 86 9.7 Yes 0
WFDC6-002 ENSP00000361750
ENST00000372665
Q9BQY6
Show all »
Show » Show » 131 14.6 Yes 0
WFDC6-201 ENSP00000470076
ENST00000600168
Q5JYQ5
Show all »
Show » Show » 161 18 Yes 0