TMEM158

GENE INFORMATION

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Gene name

TMEM158 (HGNC Symbol)

Synonyms

p40BBp, RIS1

Description

Transmembrane protein 158 (gene/pseudogene) (HGNC Symbol)

Entrez gene summary

Constitutive activation of the Ras pathway triggers an irreversible proliferation arrest reminiscent of replicative senescence. Transcription of this gene is upregulated in response to activation of the Ras pathway, but not under other conditions that induce senescence. The encoded protein is similar to a rat cell surface receptor proposed to function in a neuronal survival pathway. [provided by RefSeq, Jul 2008]

Chromosome

3

Cytoband

p21.31

Chromosome location (bp)

45265958 - 45267770

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000249992 (version 75.37)

Entrez gene

25907

UniProt

Q8WZ71 (UniProt - Evidence at transcript level)

neXtProt

NX_Q8WZ71

Antibodypedia

TMEM158 antibodies
 

PROTEIN VIEW

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TMEM158-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TMEM158-001 ENSP00000422431
ENST00000503771
Q8WZ71
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