CLDN23

GENE INFORMATION

? »

Gene name

CLDN23 (HGNC Symbol)

Synonyms

CLDNL

Description

Claudin 23 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is expressed in germinal center B-cells, placenta and stomach as well as in colon tumor. This gene is down-regulated in intestinal type gastric cancer. [provided by RefSeq, Aug 2010]

Chromosome

8

Cytoband

p23.1

Chromosome location (bp)

8559448 - 8561616

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000253958 (version 75.37)

Entrez gene

137075

UniProt

Q96B33 (UniProt - Evidence at transcript level)

neXtProt

NX_Q96B33

Antibodypedia

CLDN23 antibodies
 

PROTEIN VIEW

? »
 
 
 
CLDN23-001
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CLDN23-001 ENSP00000428780
ENST00000519106
Q96B33
Show all »
Show » Show » 292 31.9 No 3