CHMP1B

GENE INFORMATION

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Gene name

CHMP1B (HGNC Symbol)

Synonyms

C18orf2, CHMP1.5, Vps46B

Description

Charged multivesicular body protein 1B (HGNC Symbol)

Entrez gene summary

CHMP1B belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM, Mar 2008]

Chromosome

18

Cytoband

p11.21

Chromosome location (bp)

11851395 - 11854448

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000255112 (version 75.37)

Entrez gene

57132

UniProt

Q7LBR1 (UniProt - Evidence at protein level)

neXtProt

NX_Q7LBR1

Antibodypedia

CHMP1B antibodies
 

PROTEIN VIEW

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CHMP1B-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CHMP1B-001 ENSP00000432279
ENST00000526991
Q7LBR1
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