Expression of PRKCB in cancer - Staining overview

The cancer tissue page shows antibody staining in 20 different cancers. The overall cancer tissue staining statistics shows the fraction of patient samples with high, medium, low or not detected (as described by the color-coding scale in the box to the right), using all the available antibodies to the protein targets encoded by this gene. The assay and annotation is described here.

The cancers can be ordered histologically or alphabetically.

For each cancer, the staining for each available antibody is reported as the fraction of samples with antibody staining level high, medium, low or not detected (as described by the color-coding scale in the box to the right). The length of the bar represents the number of patient samples analyzed (max=12 patients). By clicking on a cancer tissue, the detailed staining data for that cancer is available, including annotated images.

At the bottom of this page, a summary for the cancer staining for each antibody is given, together with the literature conformity for the staining pattern revealed by that specific antibody.

Antibody HPA048321

Antibody CAB003843

Tissue

Antibody staining

Summary

Rare cases of carcinoid, lung and skin cancers displayed strong cytoplasmic staining. Moderate cytoplasmic positivity with additional nuclear or membranous staining was observed in few cases of urothelial and renal cancers. Remaining cancer tissues were weakly stained or negative.

Many tumors were weakly stained or negative. Most breast- and prostate cancers and several pancreatic cancers and lymphomas showed moderate to strong cytoplasmic and nuclear immunoreactivity.

Literature conformity

Partly consistent with gene/protein characterization data

Consistent with gene/protein characterization data

Level of antibody staining/expression

High
Medium
Low
Not detected

The Human Protein Atlas project is funded by the Knut & Alice Wallenberg foundation.