SERPINB3

STAINING OVERVIEW

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Overall cancer tissue 
staining statistics


0%
25%
50%
75%
100%

Tissue presentation order

Histological

Alphabetical

 

Antibody HPA048341

Antibody HPA049988

Antibody HPA055992

Antibody CAB018772

Antibody CAB036007

Tissue

Antibody staining

Antibody staining

Antibody staining

Antibody staining

Antibody staining

Colorectal cancer
Breast cancer
Prostate cancer
Ovarian cancer
Cervical cancer
Endometrial cancer
Carcinoid
Head and neck cancer
Thyroid cancer
Glioma
Lymphoma
Lung cancer
Melanoma
Skin cancer
Testis cancer
Urothelial cancer
Renal cancer
Stomach cancer
Pancreatic cancer
Liver cancer

Summary

Several of cases of colorectal, breast and prostate cancer displayed weak to moderate granular cytoplasmic immunoreactivity with additional nuclear positivity in urothelial cancers and squamous cell carcinomas. Two cases of squamous cell carcinoma of cervix showed strong staining. Remaining cancer tissues were negative.Most cancers showed weak to moderate cytoplasmic positivity with additional membranous positivity in many cases. Additional nuclear positivity was observed in squamous cell carcinomas. Cases of colorectal, endometrial, cervical, ovarian and lung cancers exhibited strong immunoreactivity. Lymphomas, renal cancers along with several cases of gliomas, melanomas and testicular cancers were negative.Cervical squamous cell carcinomas as well as cases of bladder cancers and squamous cell carcinomas in lung and skin displayed moderate to strong cytoplasmic and nuclear positivity. Remaining cancers were negative.Most squamous cell carcinomas displayed strong cytoplasmic immunoreactivity that in some cases was combined with nuclear positivity. Cases of gliomas and urothelial cancers showed moderate staining. Most of the remaining cancers were negative.Most cervical cancers along with few urothelial cancers displayed strong cytoplasmic and nuclear positivity. A few squamous cell carcinomas of skin showed moderate to strong positivity. Remaining cancers were in general negative.

Literature conformity

Consistent with extensive gene/protein characterization dataPartly consistent with extensive gene/protein characterization dataConsistent with extensive gene/protein characterization dataConsistent with extensive gene/protein characterization dataConsistent with extensive gene/protein characterization data

Level of antibody staining/expression





High
Medium
Low
Not detected