Expression of SATB2 in cancer - Staining overview

The cancer tissue page shows antibody staining in 20 different cancers. The overall cancer tissue staining statistics shows the fraction of patient samples with high, medium, low or not detected (as described by the color-coding scale in the box to the right), using all the available antibodies to the protein targets encoded by this gene. The assay and annotation is described here.

The cancers can be ordered histologically or alphabetically.

For each cancer, the staining for each available antibody is reported as the fraction of samples with antibody staining level high, medium, low or not detected (as described by the color-coding scale in the box to the right). The length of the bar represents the number of patient samples analyzed (max=12 patients). By clicking on a cancer tissue, the detailed staining data for that cancer is available, including annotated images.

At the bottom of this page, a summary for the cancer staining for each antibody is given, together with the literature conformity for the staining pattern revealed by that specific antibody.

Antibody HPA001042

Antibody HPA029543

Antibody CAB023669

Antibody CAB062562

Antibody CAB067751

Antibody CAB068229

Antibody CAB068230

Antibody CAB068231

Antibody CAB072767

Tissue

Antibody staining

Summary

Colorectal cancers and rare cases of gastric, renal and urothelial cancers displayed moderate to strong nuclear immunoreactivity. Remaining malignant cells were mainly negative.

Several colorectal cancers displayed moderate to strong nuclear positivity while renal cancers showed moderate cytoplasmic staining. Moderate cytoplasmic and nuclear staining was observed in liver cancer. Remaining malignant cells were in general negative.

Colorectal cancers displayed strong nuclear staining. A few cases of malignant lymphomas, ovarian, gastric and liver cancers displayed moderate to strong nuclear positivity. Remaining malignant cells were in general negative.

Colorectal cancers and Hodgkin's lymphomas showed moderate nuclear positivity. Remaining cancer tissues were negative.

Most colorectal cancers showed moderate to strong nuclear positivity. Other cancer tissues were negative.

Most colorectal cancers along with rare cases of renal cell carcinomas, cholangiocarcinomas and gliomas showed moderate to strong nuclear positivity. Other cancer tissues were negative.

Moderate to strong nuclear immunoreactivity was observed in most colorectal cancers. Remaining cancer tissues were negative.

Moderate to strong nuclear immunoreactivity was observed in colorectal cancers and fraction of cells in rare gliomas. Most remaining cancer tissues were negative.

Literature conformity

Consistent with extensive gene/protein characterization data

Level of antibody staining/expression

High
Medium
Low
Not detected

The Human Protein Atlas project is funded by the Knut & Alice Wallenberg foundation.