TUBA4A

GENE INFORMATION

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Gene name

TUBA4A (HGNC Symbol)

Synonyms

FLJ30169, H2-ALPHA, TUBA1

Description

Tubulin, alpha 4a (HGNC Symbol)

Entrez gene summary

Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene encodes an alpha tubulin that is a highly conserved homolog of a rat testis-specific alpha tubulin. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2013]

Chromosome

2

Cytoband

q35

Chromosome location (bp)

220114433 - 220142892

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000127824 (version 75.37)

Entrez gene

7277

UniProt

P68366 (UniProt - Evidence at protein level)

neXtProt

NX_P68366

Antibodypedia

TUBA4A antibodies
 

PROTEIN VIEW

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TUBA4A-001
 
TUBA4A-002
 
TUBA4A-003
 
TUBA4A-004
 
TUBA4A-009
 
TUBA4A-010
 
TUBA4A-011
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TUBA4A-001 ENSP00000248437
ENST00000248437
P68366
Show all »
Show » Show » 448 49.9 No 0
TUBA4A-002 ENSP00000375938
ENST00000392088
A8MUB1
Show all »
Show » Show » 433 48.3 No 0
TUBA4A-003 ENSP00000396061
ENST00000447205
C9JEV8
Show all »
Show » Show » 153 16.9 No 0
TUBA4A-004 ENSP00000416992
ENST00000456818
C9JJQ8
Show all »
Show » Show » 198 21.7 No 0
TUBA4A-009 ENSP00000404740
ENST00000425551
C9JDL2
Show all »
Show » Show » 120 13.2 No 0
TUBA4A-010 ENSP00000408194
ENST00000427737
C9JQ00
Show all »
Show » Show » 180 19.8 No 0
TUBA4A-011 ENSP00000396212
ENST00000398989
C9JDS9
Show all »
Show » Show » 156 17.7 No 0