HS3ST1

GENE INFORMATION

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Gene name

HS3ST1 (HGNC Symbol)

Synonyms

3OST1

Description

Heparan sulfate (glucosamine) 3-O-sulfotransferase 1 (HGNC Symbol)

Entrez gene summary

Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. The enzyme encoded by this gene is a member of the heparan sulfate biosynthetic enzyme family. It possesses both heparan sulfate glucosaminyl 3-O-sulfotransferase activity, anticoagulant heparan sulfate conversion activity, and is a rate limiting enzyme for synthesis of anticoagulant heparan. This enzyme is an intraluminal Golgi resident protein. [provided by RefSeq, Jul 2008]

Chromosome

4

Cytoband

p15.33

Chromosome location (bp)

11394774 - 11431389

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000002587 (version 75.37)

Entrez gene

9957

UniProt

O14792 (UniProt - Evidence at protein level)

neXtProt

NX_O14792

Antibodypedia

HS3ST1 antibodies
 

PROTEIN VIEW

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HS3ST1-001
 
HS3ST1-002
 
HS3ST1-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HS3ST1-001 ENSP00000002596
ENST00000002596
O14792
Show all »
Show » Show » 307 35.8 Yes 0
HS3ST1-002 ENSP00000422629
ENST00000510712
E9PDE3
Show all »
Show » 83 8.6 Yes 0
HS3ST1-003 ENSP00000425673
ENST00000514690
E9PDE3
Show all »
Show » 83 8.6 Yes 0