CCL18

GENE INFORMATION

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Gene name

CCL18 (HGNC Symbol)

Synonyms

AMAC-1, CKb7, DC-CK1, DCCK1, MIP-4, PARC, SCYA18

Description

Chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) (HGNC Symbol)

Entrez gene summary

This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for naive T cells, CD4+ and CD8+ T cells and nonactivated lymphocytes, but not for monocytes or granulocytes. This chemokine attracts naive T lymphocytes toward dendritic cells and activated macrophages in lymph nodes. It may play a role in both humoral and cell-mediated immunity responses. [provided by RefSeq, Sep 2014]

Chromosome

17

Cytoband

q12

Chromosome location (bp)

34391640 - 34399392

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000006074 (version 75.37)

Entrez gene

6362

UniProt

P55774 (UniProt - Evidence at protein level)

neXtProt

NX_P55774

Antibodypedia

CCL18 antibodies
 

PROTEIN VIEW

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CCL18-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CCL18-001 ENSP00000004921
ENST00000004921
P55774
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