PRSS21

GENE INFORMATION

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Gene name

PRSS21 (HGNC Symbol)

Synonyms

ESP-1, TEST1, TESTISIN

Description

Protease, serine, 21 (testisin) (HGNC Symbol)

Entrez gene summary

This gene encodes a cell-surface anchored serine protease, which is a member of the trypsin family of serine proteases. The encoded protein is predicted to be active on peptide linkages involving the carboxyl group of lysine or arginine. The encoded protein localizes to the cytoplasm and the plasma membrane of premeiotic testicular germ cells and may be involved in progression of testicular tumors of germ cell origin. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]

Chromosome

16

Cytoband

p13.3

Chromosome location (bp)

2867164 - 2876305

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000007038 (version 75.37)

Entrez gene

10942

UniProt

Q9Y6M0 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y6M0

Antibodypedia

PRSS21 antibodies
 

PROTEIN VIEW

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PRSS21-001
 
PRSS21-002
 
PRSS21-003
 
PRSS21-004
 
PRSS21-005
 
PRSS21-007
 
PRSS21-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PRSS21-001 ENSP00000005995
ENST00000005995
Q9Y6M0
Show all »
Show » Show » 314 34.9 Yes 0
PRSS21-002 ENSP00000407741
ENST00000450020
Q9Y6M0
Show all »
Show » Show » 300 33.6 Yes 0
PRSS21-003 ENSP00000460417
ENST00000570629
I3L3F7
Show all »
Show » 81 8.1 No 0
PRSS21-004 ENSP00000459664
ENST00000570594
Show » 81 8 No 0
PRSS21-005 ENSP00000458341
ENST00000574813
Show » Show » 218 24.7 No 0
PRSS21-007 ENSP00000460351
ENST00000574265
Show » Show » 256 28.6 No 0
PRSS21-201 ENSP00000400632
ENST00000455114
Q9Y6M0
Show all »
Show » Show » 312 34.6 Yes 0