PRDM1

TISSUE ATLAS

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Gene description

PR domain containing 1, with ZNF domain

RNA tissue category

Mixed.

Protein summary

Detected at High or Medium expression level in 11 of 80 analyzed normal tissue cell types.

Protein expression

Decidual cells and subset of squamous epithelial cells displayed strong nuclear staining while germinal center of tonsil showed moderate immunoreactivity. Subset of thyroid gland cells displayed strong cytoplasmic staining while cardiac myocytes showed moderate positivity. Gall bladder, gastrointestinal tract, salivary gland, respiratory epithelia, peripheral nerve and fallopian exhibited weak to moderate membranous positivity. Remaining normal tissues were negative.

Protein class

Cancer-related genes, Transcription factors

Predicted localization

Intracellular

Protein evidence

Evidence at protein level

Protein reliability

Supportive based on 1 antibody.
Liver
Colon
Kidney
Testis
Lymph node
Cerebral cortex
Esophagus
RNA Protein

Expression (FPKM)

Organ system

Localization (score)

100
50
0

h
m
l
n

Liver and pancreas
Liver
Gallbladder
Pancreas
Digestive tract (GI-tract)
N/A Oral mucosa
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Appendix
Colon
Rectum
Urinary tract (Kidney and bladder)
Kidney
Urinary bladder
Male reproductive system (Male tissues)
Testis
N/A Epididymis
Prostate
N/A Seminal vesicle
Breast and female reproductive system
N/A Breast
N/A Vagina
N/A Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Skin and soft tissues
Skin
Adipose tissue
Skeletal muscle
Smooth muscle
N/A Soft tissue
Blood and immune system (Hematopoietic)
Bone marrow
Lymph node
Tonsil
Spleen
Central nervous system (Brain)
Cerebral cortex
N/A Hippocampus
N/A Lateral ventricle
N/A Cerebellum
Endocrine glands
Thyroid gland
N/A Parathyroid gland
Adrenal gland
Respiratory system (Lung)
N/A Nasopharynx
N/A Bronchus
Lung
Cardiovascular system
Heart muscle

Antibodies in assay

HPA030033