ME1

GENE INFORMATION

? »

Gene name

ME1

Synonyms

Description

Malic enzyme 1, NADP(+)-dependent, cytosolic (HGNC Symbol)

Entrez gene summary

This gene encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet. [provided by RefSeq, Jul 2008]

Chromosome

6

Cytoband

q14.2

Chromosome location (bp)

83920108 - 84140797

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000065833 (version 75.37)

Entrez gene

4199

UniProt

P48163 (UniProt - Evidence at protein level)

neXtProt

NX_P48163

Antibodypedia

ME1 antibodies
 

PROTEIN VIEW

? »
 
 
 
ME1-001
 
ME1-201
 
ME1-202
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ME1-001 ENSP00000358719
ENST00000369705
P48163
Show all »
Show » Show » 572 64.1 No 0
ME1-201 ENSP00000439912
ENST00000541327
F5H4W0
Show all »
Show » Show » 406 44.9 No 0
ME1-202 ENSP00000446114
ENST00000543031
B4DZ70
Show all »
Show » Show » 497 55.2 No 0