UFD1L

GENE INFORMATION

? »

Gene name

UFD1L (HGNC Symbol)

Synonyms

UFD1

Description

Ubiquitin fusion degradation 1 like (yeast) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18. [provided by RefSeq, Jun 2009]

Chromosome

22

Cytoband

q11.21

Chromosome location (bp)

19437433 - 19466738

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000070010 (version 75.37)

Entrez gene

7353

UniProt

Q92890 (UniProt - Evidence at protein level)

neXtProt

NX_Q92890

Antibodypedia

UFD1L antibodies
 

PROTEIN VIEW

? »
 
 
 
UFD1L-001
 
UFD1L-003
 
UFD1L-006
 
UFD1L-007
 
UFD1L-008
 
UFD1L-009
 
UFD1L-201
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

UFD1L-001 ENSP00000263202
ENST00000263202
Q92890
Show all »
Show » Show » 307 34.5 No 0
UFD1L-003 ENSP00000382439
ENST00000399523
Q92890
Show all »
Show » Show » 266 29.9 No 0
UFD1L-006 ENSP00000406680
ENST00000421968
C9IZG3
Show all »
Show » Show » 190 21.7 No 0
UFD1L-007 ENSP00000402136
ENST00000447868
C9JNP9
Show all »
Show » Show » 159 17.6 No 0
UFD1L-008 ENSP00000418295
ENST00000474226
C9J7C8
Show all »
Show » Show » 69 7.9 No 0
UFD1L-009 ENSP00000418390
ENST00000494054
C9J6N9
Show all »
Show » Show » 136 15.5 No 0
UFD1L-201 ENSP00000354079
ENST00000360834
A6NJ11
Show all »
Show » Show » 296 33.3 No 0