NME8

GENE INFORMATION

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Gene name

NME8 (HGNC Symbol)

Synonyms

CILD6, NM23-H8, SPTRX2, TXNDC3

Description

NME/NM23 family member 8 (HGNC Symbol)

Entrez gene summary

This gene encodes a protein with an N-terminal thioredoxin domain and three C-terminal nucleoside diphosphate kinase (NDK) domains, but the NDK domains are thought to be catalytically inactive. The sea urchin ortholog of this gene encodes a component of sperm outer dynein arms, and the protein is implicated in ciliary function. Mutations in this gene are implicated in primary ciliary dyskinesia type 6.[provided by RefSeq, Nov 2009]

Chromosome

7

Cytoband

p14.1

Chromosome location (bp)

37888199 - 37940003

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000086288 (version 75.37)

Entrez gene

51314

UniProt

Q8N427 (UniProt - Evidence at protein level)

neXtProt

NX_Q8N427

Antibodypedia

NME8 antibodies
 

PROTEIN VIEW

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NME8-001
 
NME8-002
 
NME8-003
 
NME8-004
 
NME8-005
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NME8-001 ENSP00000199447
ENST00000199447
Q8N427
Show all »
Show » Show » 588 67.3 No 0
NME8-002 ENSP00000397063
ENST00000440017
Q8N427
Show all »
Show » Show » 588 67.3 No 0
NME8-003 ENSP00000390047
ENST00000455500
C9JIT0
Show all »
Show » 116 12.9 No 0
NME8-004 ENSP00000390596
ENST00000444718
C9JG62
Show all »
Show » Show » 150 16.8 No 0
NME8-005 ENSP00000408841
ENST00000426106
F8WEA2
Show all »
Show » 54 6.4 No 1