AAAS

TISSUE ATLAS

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Gene description

Achalasia, adrenocortical insufficiency, alacrimia

RNA tissue category

Expressed in all.

Protein summary

Detected at High or Medium expression level in 26 of 81 analyzed normal tissue cell types.

Protein expression

Cells in seminiferus ducts, placental trophoblasts, renal tubules, thyroid and adrenal glands showed strong cytoplasmic immunoreactivity. Lymphoid tissues, male genitalia tract, myocytes, neuropil and subsets of cells in the CNS showed moderate to strong cytoplasmic positivity. Hepatocytes and ductal cells in salivary gland showed strong membranous positivity. Remaining normal tissues were in general weakly stained or negative.

Protein class

Disease related genes

Predicted localization

Intracellular

Protein evidence

Evidence at protein level

Protein reliability

Uncertain based on 1 antibody.
Liver
Colon
Kidney
Testis
Lymph node
Cerebral cortex
Adrenal gland
RNA Protein

Expression (FPKM)

Organ system

Localization (score)

100
50
0

h
m
l
n

Liver and pancreas
Liver
Gallbladder
Pancreas
Digestive tract (GI-tract)
N/A Oral mucosa
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Appendix
Colon
Rectum
Urinary tract (Kidney and bladder)
Kidney
Urinary bladder
Male reproductive system (Male tissues)
Testis
N/A Epididymis
Prostate
N/A Seminal vesicle
Breast and female reproductive system
N/A Breast
N/A Vagina
N/A Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Skin and soft tissues
Skin
Adipose tissue
Skeletal muscle
Smooth muscle
N/A Soft tissue
Blood and immune system (Hematopoietic)
Bone marrow
Lymph node
Tonsil
Spleen
Central nervous system (Brain)
Cerebral cortex
N/A Hippocampus
N/A Lateral ventricle
N/A Cerebellum
Endocrine glands
Thyroid gland
N/A Parathyroid gland
Adrenal gland
Respiratory system (Lung)
N/A Nasopharynx
N/A Bronchus
Lung
Cardiovascular system
Heart muscle

Antibodies in assay

HPA040086