POLR2E

GENE INFORMATION

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Gene name

POLR2E (HGNC Symbol)

Synonyms

hRPB25, hsRPB5, RPABC1, RPB5, XAP4

Description

Polymerase (RNA) II (DNA directed) polypeptide E, 25kDa (HGNC Symbol)

Entrez gene summary

This gene encodes the fifth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA polymerases and is present in two-fold molar excess over the other polymerase subunits. An interaction between this subunit and a hepatitis virus transactivating protein has been demonstrated, suggesting that interaction between transcriptional activators and the polymerase can occur through this subunit. A pseudogene is located on chromosome 11. [provided by RefSeq, Jul 2008]

Chromosome

19

Cytoband

p13.3

Chromosome location (bp)

1086594 - 1095598

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000099817 (version 75.37)

Entrez gene

5434

UniProt

P19388 (UniProt - Evidence at protein level)

neXtProt

NX_P19388

Antibodypedia

POLR2E antibodies
 

PROTEIN VIEW

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POLR2E-001
 
POLR2E-002
 
POLR2E-006
 
POLR2E-010
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

POLR2E-001 ENSP00000215587
ENST00000215587
P19388
Show all »
Show » Show » 210 24.6 No 0
POLR2E-002 ENSP00000465066
ENST00000591767
K7EJ87
Show all »
Show » Show » 68 7.5 No 0
POLR2E-006 ENSP00000467905
ENST00000589737
K7EQN2
Show all »
Show » Show » 51 6.1 No 0
POLR2E-010 ENSP00000464739
ENST00000586746
P19388
Show all »
Show » Show » 210 24.6 No 0