EFS

GENE INFORMATION

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Gene name

EFS (HGNC Symbol)

Synonyms

CASS3, EFS1, EFS2, HEFS, SIN

Description

Embryonal Fyn-associated substrate (HGNC Symbol)

Entrez gene summary

The longest protein isoform encoded by this gene contains an SH3 domain, which is known to be important in intracellular signal transduction. The protein encoded by a similiar gene in mice was shown to bind to SH3 domains of protein-tyrosine kinases. The function of this gene is unknown. Three alternatively spliced variants encoding different isoforms have been described for this gene. [provided by RefSeq, Mar 2013]

Chromosome

14

Cytoband

q11.2

Chromosome location (bp)

23825611 - 23834961

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000100842 (version 75.37)

Entrez gene

10278

UniProt

O43281 (UniProt - Evidence at transcript level)

neXtProt

NX_O43281

Antibodypedia

EFS antibodies
 

PROTEIN VIEW

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EFS-001
 
EFS-003
 
EFS-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

EFS-001 ENSP00000340607
ENST00000351354
O43281
Show all »
Show » Show » 468 49 No 0
EFS-003 ENSP00000216733
ENST00000216733
O43281
Show all »
Show » Show » 561 58.8 No 0
EFS-201 ENSP00000416684
ENST00000429593
B4DJ56
Show all »
Show » 392 41 No 0