TNFSF13B

GENE INFORMATION

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Gene name

TNFSF13B (HGNC Symbol)

Synonyms

BAFF, BLYS, CD257, TALL-1, TALL1, THANK, TNFSF20

Description

Tumor necrosis factor (ligand) superfamily, member 13b (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011]

Chromosome

13

Cytoband

q33.3

Chromosome location (bp)

108903588 - 108960832

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000102524 (version 75.37)

Entrez gene

10673

UniProt

Q9Y275 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y275

Antibodypedia

TNFSF13B antibodies
 

PROTEIN VIEW

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TNFSF13B-001
 
TNFSF13B-201
 
TNFSF13B-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TNFSF13B-001 ENSP00000365048
ENST00000375887
Q9Y275
Show all »
Show » Show » 285 31.2 No 0
TNFSF13B-201 ENSP00000389540
ENST00000430559
Q9Y275
Show all »
Show » Show » 266 29.1 No 0
TNFSF13B-202 ENSP00000445334
ENST00000542136
Q9Y275
Show all »
Show » Show » 164 17.6 No 1